PGD
Through Preimplantation Genetics Diagnosis (PGD), VCRM helps patients to achieve their goal of having a healthy baby in collaboration with RMS Genetics, a leading ART and Genetics Center.
While almost any IVF patient can benefit from PGD, it is of critical importance to the following two patient groups:
- Couples with infertility related to recurrent pregnancy loss or failed IVF cycles.
- Couples who are at risk for passing on inherited genetic disease to their offspring
PGD Technique
PGD is performed as a part of an In Vitro Fertilization cycle where multiple eggs are produced, retrieved from the ovaries and fertilized with the partner's sperm in the Embryology Laboratory. IVF gives us access to embryo(s) in vitro. PGD is then performed by removing one or two cells from each embryo through a procedure called embryo biopsy. These cells are then transported to RMA-NJ and analyzed in the RMA Genetics Laboratory for the presence of genetic disorders and chromosomal abnormalities. This sophisticated and technologically advanced testing attempts to identify embryos which are free of abnormalities and more able to achieve the patient's goal of a healthy baby.
PGD technology IDENTIFIES GENETIC ABNORMALITIES IN EMBRYOS
Chromosomal abnormalities in early embryonic cells are analyzed in Laboratory by fluorescence in situ hybridization (FISH) to determine proper structure and the appropriate number of the chromosomes tested. Inherited Single Gene Disorders are analyzed in collaboration with a contracted laboratory.
- PGD & INFERTILITY
- Recurrent Pregnancy Loss
- Advanced Maternal Age
- Male Infertility
- Repeated IVF Failure
- STRUCTURAL ABNORMALITIES
- Translocations
- Inversions
- Deletions
- INHERITED SINGLE-GENE DISORDERS
We currently have the ability to analyze up to nine chromosomes (13, 15, 16, 17, 18, 21, 22, XY).
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