Specialized Options

Specialized tools for specific clinical questions.

VCRM offers several specialized technologies and protocols. This page explains what each tool is designed to address so patients can discuss whether it applies to their case.

Personalized Care

Every cycle is managed directly by Dr. Sharara with dedicated one-on-one monitoring.

Schedule Visit (703) 437-7722
Single Embryo Transfer

Elective Single Embryo Transfer (eSET)

After the retrieval and fertilization of eggs using In Vitro Fertilization (IVF), patients with multiple high-quality embryos may elect to have a single embryo transferred to the uterus (eSET) even when multiple embryos are available. At VCRM, 100% of our embryo transfers are performed at Day 5 (or Day 6 for fresh PGS cycles).

Our "take-home baby rate" with eSET is around 60%, and increases to around 80% when combining PGT/PGS genetic testing with eSET. Our ongoing/delivered pregnancy rate across eligible eSET candidates is approximately 65%.

The primary goal of eSET is to eliminate the risks associated with multiple pregnancies (twins, triplets, quadruplets). In the U.S., approximately 30% of standard IVF pregnancies result in twins and 3–4% result in triplets or higher-order multiples. Transferring a single top-quality blastocyst provides maximum pregnancy success while preventing premature delivery and neonatal complications.

ASRM Patient Video: Risks of Multiple Pregnancies & the Benefits of eSET
Candidate Criteria Age < 38 years, 1st or 2nd ART cycle, prior ART success, multiple high-quality blastocysts available.
Cryopreservation Remaining high-quality blastocysts are frozen for future sibling transfers.
Monozygotic Risk There is a low (1.5%) chance of identical twin splitting after transfer.
Exclusive Blastocyst Culture

100% Day 5 Blastocyst Transfer Policy

Multiple scientific studies confirm that blastocyst transfers (BT) on Day 5 achieve equivalent or superior pregnancy rates compared to Day 3 transfers, despite replacing significantly fewer embryos. While traditional Day 3 transfers replace 3–4 embryos, a Day 5 transfer typically replaces only 1 or 2 blastocysts.

A blastocyst is a 5-day-old embryo containing ~100 cells separated into two distinct cell types: the inner cell mass (which forms the baby) and the trophectoderm (which forms the placenta). The blastocyst hatches from its Zona Pellucida (egg shell) around Day 6 and implants in the uterus.

Exclusive Distinction: Between 2003 and 2012, VCRM utilized blastocyst transfers for over 75% of patients (achieving a 68% pregnancy rate across ages 21–45). Since March 2013, VCRM performs blastocyst transfers exclusively in 100% of cases, making us the ONLY fertility center in the Washington-Baltimore-Richmond-Norfolk regional area with an exclusive 100% blastocyst transfer policy.

Precision IVF

Continuous embryo monitoring & CHLOE technology

Precision IVF uses time-lapse embryo monitoring so development can be observed without disturbing the incubator environment. The patient-facing CHLOE platform provides transparent embryo video logs and detailed cycle reports.

DuoStim Protocol

Dual ovarian stimulation in a single cycle

DuoStim involves ovarian stimulation in both the follicular and luteal phases of the same menstrual cycle, allowing two egg retrievals in a shorter timeframe for low responders or urgent fertility preservation.

Next Step

Discuss Advanced Care Protocols with Dr. Sharara

Schedule a consultation to evaluate whether eSET, blastocyst culture, or Precision IVF is best suited for your treatment plan.

Personalized Care

Every cycle is managed directly by Dr. Sharara with dedicated one-on-one monitoring.

Schedule Visit (703) 437-7722