A focused treatment when sperm placement and timing are the main barriers.

Intrauterine insemination with washed semen, abbreviated IUI, is a technique that places prepared sperm directly into the uterus using a catheter. During intercourse, sperm are placed in the vagina, travel through the cervical mucus into the uterus, and then into the fallopian tubes where conception occurs. IUI bypasses the vagina and cervix where many sperm are otherwise lost, significantly increasing the number of motile sperm available to fertilize an egg.

To prepare sperm for IUI, a semen sample is obtained and expertly processed in our state-of-the-art laboratory. The liquid semen is separated from the sperm, and the sperm are "washed" and re-suspended in a specially prepared solution. This process concentrates the motile sperm and removes uterine irritants contained in semen, making intrauterine insemination safer, more effective, and comfortable.

Success rates vary depending on the couple’s original diagnosis, age, and number of IUI cycles. The pregnancy rate per cycle of insemination is 15–20%. The cumulative pregnancy rate may reach 30–50% in couples undergoing three cycles.

The use of fertility medications increases the chance of pregnancy:

• Oral Medications (Clomid / Tamoxifen / Letrozole): Pregnancy rate is approximately 10–15% per cycle, with a multiple pregnancy rate of about 5% (mostly twins).
• Injectable Gonadotropins: Pregnancy rate is approximately 15–18% per cycle, with a multiple pregnancy rate of 20–25% (some higher-order multiples such as triplets).

Note: These success rates are age-dependent and are significantly lower in women over age 35.

For injectable medication guides and instructions, patients can review the Ferring Fertility Menopur Training Guide.